Doctor Strange, the Sorcerer Supreme in the Marvel Universe, faces a variety of mystical and otherworldly adversaries. Here are some of the main enemies that Doctor Strange has encountered in the comics:

1. **Dormammu:**
– A powerful and malevolent entity from the Dark Dimension, Dormammu is one of Doctor Strange’s most iconic and recurrent foes. He possesses vast mystical abilities and seeks to conquer various dimensions, often clashing with Doctor Strange in the process.

2. **Baron Mordo (Karl Mordo):**
– Once a fellow student of the Ancient One, Mordo becomes one of Doctor Strange’s primary adversaries. He is a skilled sorcerer who often opposes Strange, driven by his thirst for power and the desire to surpass the Sorcerer Supreme.

3. **Shuma-Gorath:**
– A monstrous and ancient entity, Shuma-Gorath is a powerful force that exists in various dimensions. Doctor Strange has faced this cosmic horror in battles that test his magical prowess and understanding of the mystic arts.

4. **Mephisto:**
– Mephisto is a demonic entity often associated with deals and bargains. While primarily a foe of characters like Ghost Rider, Mephisto has crossed paths with Doctor Strange, engaging in mystical conflicts and manipulations.

5. **Nightmare:**
– As the ruler of the Dream Dimension, Nightmare is a demonic being who feeds on the fear of sleeping beings. Doctor Strange often confronts Nightmare in the realm of dreams, where the villain seeks to trap and torment his victims.

6. **The Mindless Ones:**
– Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

7. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures associated with dark dimensions. Doctor Strange has encountered them in various storylines, and they pose a formidable physical threat due to their sheer strength and lack of independent thought.

8. **The Dread Dormammu’s Mindless Ones are powerful, otherworldly creatures